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The University of British Columbia (UBC) is Canada’s third largest university and consistently ranks among the 40 best universities in the world. Primarily situated in Vancouver, UBC is a research-intensive university and has an economic impact of $4 billion to the provincial economy. 


Postdoctoral Research Fellow: Epigenetics and Asthma

BC Children's Hospital Research Institute

Department of Pediatrics, Faculty of Medicine

University of British Columbia

Temporary Full Time (one year term)

Vancouver, BC


Asthma is the most common chronic non-communicable disease. Asthma typically begins in childhood and lasts throughout life. The numbers are striking: asthma affects ~13% of children (~500,000 in Canada) and more than 3 million Canadians of all ages. This high prevalence, combined with significant asthma-related morbidity, leads to a heavy economic and human burden of asthma in Canada and worldwide.


Epigenetics offers a mechanism by which environmental exposures in early life can get “under the skin” to regulate the activity of genes relevant to asthma. DNA methylation, an epigenetic mechanism used by cells to control gene expression, is highly changeable during prenatal development and early life, and some of these changes have been correlated to early life events, including the gut microbiome and other environmental exposures. Our goal is to define the relationship between early life environmental exposures, epigenetics, gene expression and clinical outcomes leading to the diagnosis of childhood asthma. 


A postdoctoral position is available to join an energetic and collegial group dedicated to enhancing the health of children. The successful applicant will work at the BC Children's Hospital Research Institute on this exciting collaborative project directed by Drs. Stuart Turvey and Michael Kobor. This position will be translational and interdisciplinary in nature aimed at examining whole genome DNA methylation and global gene expression in a large birth cohort dedicated to defining the origins of asthma. 


Applicants should have a recent (<2 years) PhD or MD/PhD with a strong background and publication record in a relevant field (e.g. immunology, genetics, molecular biology). The position will rely heavily on statistical analyses so demonstrated expertise in statistical analysis is required. In addition, either experience in epigenetics or in processing of microarray data would be an asset. 


The position will commence as soon as possible. 


The initial appointment will be for a one-year term, with potential for annual renewal. 


Salary will be commensurate with qualifications and experience. 


Qualified candidates should send (by email) a statement of research interest, curriculum vitae and contact details for 3 referees to: 


Stuart Turvey MB BS DPhil FRCPC

BC Children's Hospital Research Institute

University of British Columbia

950 West 28 Avenue

Vancouver BC V5Z 4H4 



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